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Category:Music softwareChanges in gene expression of Toll-like receptor 3 and inducible nitric oxide synthase in rat liver in endotoxemia.
Previously, we reported that Toll-like receptor 3 (TLR3) is expressed in rat liver, suggesting a possible role in the pathogenesis of septic liver injury. Here, we studied changes in TLR3 expression and related factors in liver of rats with endotoxemia. Male Sprague-Dawley rats were injected with lipopolysaccharide (LPS) intraperitoneally, and the levels of serum aspartate aminotransferase and alanine aminotransferase, tumor necrosis factor (TNF)-alpha, TLR3, and inducible nitric oxide synthase (iNOS) in liver tissue were determined. In normal liver, TLR3 was weakly expressed, and the expression of TNF-alpha, TLR3, and iNOS was increased by LPS injection. In LPS-treated rats, liver weight, serum aspartate aminotransferase and alanine aminotransferase levels, and the expression of TNF-alpha, TLR3, and iNOS were increased, and the expression of iNOS was decreased. The present data suggest that the LPS-TLR3 pathway may be involved in the development of LPS-induced hepatic damage, and TLR3 may play a part in mediating the inflammatory response.Q:
Single Word for 'Someone Who Is Meant To Have Something but Does Not'
I am looking for a single word to describe someone who is meant to have something, but does not.
Say, someone who is meant to have the key to the school but does not.
A:
"Burden-bearer" or "custodian" seem to fit your description, although it sounds more formal than most people would like to use.
A:
Seems to fit.
"Someone who is a custodian of something"
Or
"Someone who is responsible for the preservation and the safety of something"
Can be used in the context you are describing.
Q:
Spark cannot find SparkSession, even when running from spark ac619d1d87
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